Frequently Asked Questions



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General Questions

CBD or Cannabidiol is just one of the many components of the cannabis plant. Studies have shown that CBD contains anti-inflammatory qualities, on top of other various health benefits. It is commonly used to promote overall wellness and at the same time it is non-intoxicating.
It is just one of many different molecules known as cannabinoids found in the cannabis plant. 
CBD (or Cannabidiol) is one of over 100 active compounds found in the cannabis plant and is known for its interaction with our Endocannabinoid System when ingested.

In the cannabis industry, the word “tincture” and “oil” are used interchangeably. A CBD tincture is just another term for a CBD oil.

A CBD tincture or CBD oil is a liquid concentrate that contains CBD.

Cannabinoids are active compounds produced by the cannabis plant which both promote and support nutritional health.. They account for most of the benefits of cannabis. Our body also produces cannabinoids on its own (like anandamide). Those are called endocannabinoids while cannabinoids produced by the cannabis plant are called phytocannabinoids.
When we supplement Cannabinoids, they interact with the body’s Endocannabinoid system (or ECS), which promotes homeostasis (or simply balance) in our body.

The human EndoCannabinoid System, or ECS, is a system of two components. One component are neurotransmitters – the cannabinoids produced by our body’s central nervous system called endocannabinoids. The other component are cell membrane receptors found on the surface of cells throughout the body. Neurotransmitters (cannabinoids) interact with cannabinoid receptors on cell membranes to adjust physiological processes at a cellular level.

The endocannabinoid system is vast and far-reaching. It regulates a wide array of bodily functions, from appetite regulation to sleep patterns, moods, metabolism, immune response, the lifespan of cells and much more.

For example, a well-known endocannabinoid is called anandamide. Anandamide is responsible for the production and uptake of the hormone called Serotonin. Serotonin is often referred to as the “bliss molecule” because levels of Serotonin in the body are directly associated with mood.

The Entourage effect is the reason why all PAPILO products are made with Full Spectrum CBD extract. Full Spectrum CBD extract contains a variety of cannabinoids and terpenes as well as other beneficial compounds of the cannabis plant. 

Each of the compounds has particular effects on the human body and the combined effect is often greater than the sum of the individual effects. The synergistic effect of the combined components is known as the Entourage Effect. Products made with CBD isolate do not have the benefit of the entourage effect and are therefore much less beneficial.

Hemp as a cannabis plant variety is used for a lot of things. 

As a nutritional supplement it’s used for extracting flowers. The basic outcome is a CBD rich Full Spectrum extract. And as a full spectrum CBD extract it also includes other cannabinoids (yes, including small amounts of THC), terpenes and other components found in the Hemp plant.

Hemp seeds are used to produce Hemp seed oil. It has no cannabinoids and is mostly used as a culinary oil. Compared with other culinary oils, hemp seed oil is low in saturated fat and rich in polyunsaturated fat. 

Hemp seed oil is sometimes referred to as simply Hemp oil. So it can get quite confusing when you are trying to buy Full Spectrum CBD. If you are looking for Full Spectrum CBD products be careful not to buy products that contain just Hemp Seed oil and zero cannabinoids!

For other industries, hemp stems and leaves can be processed into cloth, rope, plastic, fuel and many other useful things.

Hemp Oil is usually referred to as an extract made from hemp flowers. Hamp is a cannabis plant with less than 0.3% THC. The extract from flowers of some hemp strains is rich with CBD and other cannabinoids and has a very low amount of THC.

However some manufacturers also use the term Hemp Oil for their Hemp SEED Oil. This is of course confusing as the customers think they are getting Hemp Oil as Full Spectrum CBD product but in fact they are getting only the “culinary” Hemp Seed oil with no cannabinoids.

Here’s a video that will explain exactly the difference between Hemp CBD oil and Hemp Seed oil:

Hemp as a cannabis strain variety has only trace amounts of THC. Usually below 0.3%. So if you take the flowers to smoke it will not get you high because there’s not enough THC.

However when you take those same flowers and make a basic Full Spectrum extract, that extract is a concentrated liquid. Therefore the THC in that liquid is also concentrated. As a result it’s possible for hemp to get you high.

However (one more however 😉 all of our products are made with a small amount of the Full Spectrum Extract (concentrate) in the final product and it also has recommended doses. With all that combined it’s unlikely you will feel the high.

If the Hemp product is Hemp Seed Oil it does not contain cannabinoids and will most certainly not get you high.

It’s very important that you know exactly what you are getting when buying “hemp” products so read through product descriptions, labels and details.
We always recommend products made with Full Spectrum CBD extract as they tend to give you the best results.

Yes it does. Hemp is a cannabis plant variety that has traces amounts of THC – below 0.3%

There are many great CBD brands on the market today.
Nevertheless we recommend that you look for a brand that uses Full Spectrum CBD extract in their product as does our PAPILO brand. This will ensure you get the most out of the CBD products because the Full Spectrum components will have a synergistic effect in your body known as the Entourage effect.

It’s probably a good idea to ask around and get a recommendation of what brand you should choose.

In terms of getting someone “high” or “stoned” like THC, CBD is not psychoactive.

The cannabis plant consists of a wide variety of chemicals and compounds. Terpenes are essential oils found in plants. There are around 200 terpenes in cannabis. They are what gives cannabis its distinct aroma and flavor. Terpenes have beneficial effects and work synergistically with cannabinoids like CBD and THC – this relationship is called the entourage effect. 

The FDA and other agencies have generally recognized terpenes as “safe.”

Cannabis is a plant species. So both Hemp and Marijuana are Cannabis.

Hemp is Cannabis plant with THC levels below 0.3%.

Marijuana is Cannabis plant with THC levels above 0.3%.

Several scientific studies have shown that the best CBD oil is a Full-Plant extract or Full Spectrum CBD which contains terpenes and flavonoids naturally occurring in cannabis. All of the extracted plant components work synergistically and can give an enhanced effect.

There are many different ways to use CBD. The four main ways are:
1) Sublingual  – Oils Tinctures and Sprays
2) Topical – Lotions and Balms
3) Oral – Edibles and Capsules
4) Inhalation – Vaporization or Smoking. 

The administration will depend on your needs.  

The fastest way to feel the effect is inhalation. But the effect is not long-lasting.

Sublingual also enters the body fast and since part of the CBD (after holding it under your tongue for 30 to 60 seconds) is swallowed it “becomes” oral and thus gives you that long-lasting effect as well.

Topical is mostly for your skin as most of the CBD does not penetrate deep into the body.

With oral administration, the effect will be felt after 30 to 60 minutes but it’s long-lasting.

CBD drops and CBD Chocolates are the easiest, most convenient and last the longest.

This way it’s also very easy to measure the exact amount of CBD you are taking.

Medical cannabis, or medical marijuana, can refer to the use of cannabis to treat disease or improve symptoms. However, there is no single agreed-upon definition. Mostly, this term is used to define plants that contain high amounts of THC, but it is becoming more complicated to define what it is, due to the fact that we have recently found a lot of cannabis plants with many other molecules.

Medical cannabis or medical marijuana is a word used very frequently in the thousands of medical cannabis shops in the USA where they sell cannabis plants legally under state law. Most of the medical cannabis / medical marijuana is sold for recreational purposes.

Tetrahydrocannabinol (THC) is the cannabinoid found most in abundance in the cannabis plant. It has a psychoactive effect, hence plant varieties that have been bred for recreational use are particularly high in THC.

That is not to say that THC doesn’t have any therapeutic use. It has been found to be effective for reducing nausea and vomiting experienced by patients during chemotherapy, can slow down the progression of glaucoma and help reduce nerve pain.

CBD Oil extracted from Hemp contains:

CBD, Chlorophyll, Alkanes, Nitrogenous compounds, Amino acids, Sugars, Aldehydes, Alcohols, Ketones, Flavonoids, Glycosides, Vitamins, and Pigments.

Research has shown that Hemp contains over 400 different molecules. Recent research shows there is a group of molecules that cannabis produces called cannabinoids, which are mostly responsible for its effects. There are over 120 cannabinoids including CBD, THC, CBG, CBC, and CBN.

A famous cannabinoid is THC, which is psychoactive and responsible for the high. CBD products however usually contain only traces amounts of THC, not enough to get you high.

CBD can be taken either way. If you want to maximize absorption, or if you have a sensitive stomach, it is best to take CBD with meals or within an hour of eating. A few human studies have found increased absorption from the gastrointestinal tract when it is taken with food, especially fatty foods. Studies have also shown CBD taken orally when combined with lipids to increased systemic availability by almost threefold!

CBD has been shown to lessen anxiety in humans, and it does so through actions on a variety of brain receptors but primarily those for serotonin. One study shows CBD has a rapid-onset antidepressant effect on the brain by promoting changes in synaptic plasticity and the release of growth factors such as BDNF (brain-derived neurotrophic factor). This study was on mice, but CBD is thought to have similar effects on the human brain which may contribute to its mood-boosting effects, along with actions at the serotonin receptors.

To extract CBD-rich cannabis oil, you must start with CBD-rich plant material. 

There are many ways to extract oil from the cannabis plant, each has its pros and cons. Some methods are safer and more effective than others. 

Cannabis oils made with neurotoxic solvents like butane and hexane may leave unsafe residues that interfere with immune function and impede healing. 

Supercritical CO2 extraction is non-toxic and produces high-quality oil, but requires significant expertise and access to expensive equipment. 

If you want to extract CBD your self you can also use safer solvents, such as ethanol, or prevent exposure to organic solvents entirely by using olive oil to extract cannabis oil, according to Dr. Arno Hazekamp director of phytochemical research at Bedrocan BV, which supplies cannabis, including a CBD-rich strain, for the Dutch Health Ministry’s medical marijuana program.

By juicing or otherwise ingesting raw, unheated cannabis, you consume CBD and the other cannabinoids in their acid form. A CBD-rich strain contains CBD-acid (CBDA), which, when heated, becomes CBD. 

Nevertheless, unheated CBDA and other cannabinoids do have medicinal attributes and are indeed very good for the human body.

Product Related Questions

We grow our hemp 100% organically.

If you are going to use it starting today and on a daily basis it’s okay to have your CBD at room temperature.
If you want to store it for later use it’s best to store it in the refrigerator.

We are proud to say we grow our own Hemp, make our own extracts and make our own final products. Our production is from seed to final product. 

Most drug tests in the workplace search for the intoxicating compound THC, not Cannabidiol (CBD) or other compounds found naturally in hemp.

With that being said, our Full Spectrum CBD products have at most 0.3% THC content in them, making it extremely unlikely for it to result in a failed drug test. It can also depend on the kind of drug test that is administered, as some are more thorough than others.

With full-spectrum CBD, it’s theoretically possible to get a false-positive result for THC, but in order to do so, a person would need to take around 2,000 mg of CBD oil daily. Most people never exceed 100 mg.

We like to take great care of our customers. So we will talk to you via email about what you need for your specific issue and what would be the best way for you to take it.

Absolutely. However we do recommend making a 1 to 2 weeks break for your Endocannabinoid system to work on its own and “upgrade”.

Refrigerated CBD oil will be good for years.
If not refrigerated it will be good for at least one year.

You do need to be older than 18.

Order Related Questions

We ship worldwide.

We only ship with DHL Express as that is by far the best and the most reliable service we’ve come across.

Of course. We offer a 30 day money back guarantee. If you are not happy with our products simply send them back and we will refund you in full. Here are return policy details.

Please contact us via email (support at and we will make sure we take great care of you.

Simply send us an email to (support at

We offer a free worldwide shipping on all orders over $100.

About 3-6 days depending on where the order is sent to.

Simply – we offer a 30 day money back guarantee. If you are not happy with our products simply send them back and we will refund you in full. Here are return policy details –

Safety Related Questions

No. CBD does not get you high. It is 100% non-psychoactive. 

Drug tests do not detect CBD oil (cannabidiol). Drug tests are designed to pick up on THC. 

As our CBD products contain almost untraceable amounts of THC (0.3% or less), this is not enough to make you high or even test positive for using drugs.

No. Drug tests look for THC, the psychoactive cannabinoid found in marijuana. Drug tests do not test for specifically CBD. 

It’s important to remember that while CBD is safe for you to use, it can potentially interfere with other medications. This is because of how CBD is metabolized by your body and the possibility that it can alter how your body normally metabolizes your other medication.

If your medication isn’t metabolized properly, the medication might not work. Instead, it may stay in your system longer than desired, or in a form that your body doesn’t like, leading to negative side effects and potential complications. For example, taking CBD with blood thinners can maybe result in them not breaking down in your system. However, there’s a chance that CBD can make your medication more effective – so much so that you might even be able to reduce your regular medication dosage.

The trick is to ask your doctor or medical professional if you can take grapefruit with your medication. Grapefruits can also mess with the metabolism of a variety of medications, so if your doctor says no to grapefruit then you’ll have to be careful about mixing CBD with your medication. Of course, we always recommend discussing CBD with your doctor anyway – especially if you’re already taking medication. To find out more, read our resource on the potential effects of CBD.

CBD has been shown to be safe to use in high doses. CBD will not cause a fatal overdose. However, it is possible to take too much CBD. A consequence of taking too much CBD is the increased chance of negative side effects like lethargy or drowsiness.

CBD is not known to be an addictive substance. In fact, CBD has shown strong potential to be a useful tool to help people break addictions to harmful substances like alcohol or opiates.

– CBD exhibits no effects on humans indicative of any abuse or dependence potential.

– To date, there is no evidence of recreational use of CBD or any public health-related problems associated with the use of pure CBD.

– Chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.

Source: World Health Organization, WHO Expert Committee on Drug Dependence, Thirty-ninth Meeting Geneva, 6-10 November 2017.

Safety and side effects of cannabidiol (NCBI/NIH). Curr Drug Saf. 2011 Sep 1;6(4):237-49.  Safety and side effects of cannabidiol, a Cannabis sativa constituent. Bergamaschi MM(1), Queiroz RH, Zuardi AW, Crippa JA

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